Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | TEK | Q02763 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481076 | 0.87 | EGFR (0.78) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL2747998 | 0.85 | PDGFRB (0.71) | EGFRPDGFRBPDGFRAKDRAURKA | |
| SCHEMBL19373176 | 0.85 | EGFR (0.74) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL31061546 | 0.85 | EGFR (0.74) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL167396 | 0.85 | PDGFRA (0.74) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL17117826 | 0.84 | FGFR2 (0.78) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL31060325 | 0.84 | FGFR2 (0.78) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL7490337 | 0.84 | EGFR (0.72) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL31060866 | 0.84 | EGFR (0.72) | EGFRPDGFRBPDGFRAKDRFGFR2 | |
| SCHEMBL31060617 | 0.84 | EGFR (1.00) | EGFRPDGFRBPDGFRAKDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2017049462-A1 | NOVEL FLT3 KINASE INHIBITOR AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-03-30 | — | — | WO | disclosed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |