⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL27971501 | 1.00 | ALDH1A1 (0.87) | — | |
| Imidazole SCHEMBL29090528 | 0.97 | — | — | |
| Imidazole SCHEMBL30382963 | 0.93 | — | — | |
| Imidazole SCHEMBL28744226 | 0.93 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL19028065 | 0.93 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL2684565 | 0.93 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL897 | 0.93 | — | — | |
| Imidazole SCHEMBL2635292 | 0.93 | — | — | |
| Imidazole SCHEMBL1331920 | 0.93 | — | — | |
| Imidazole SCHEMBL1331382 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114888-A1 | DESIGN OF LIGAND ATTACHMENT CHEMISTRY FOR HIGH CONDUCTIVITY POLYMER ELECTROLYTES | The Regents of University of California (US) | 2023-01-11 | — | — | EP | disclosed |
| US-20210284805-A1 | DESIGN OF LIGAND ATTACHMENT CHEMISTRY FOR HIGH CONDUCTIVITY POLYMER ELECTROLYTES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | US | disclosed |
| CN-109153649-A | The allosteric modulators of nicotinic acetylcholine receptor | 默沙东公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-106222185-A | Glucanase, the nucleic acid encoding them and preparation and their method of use | 维莱尼姆公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-106011159-A | Phytases, nucleic acids encoding them and methods for making and using them | 巴斯夫酶有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-102459303-B | Phytases, nucleic acids encoding them and methods of making and using them | 巴斯夫酶有限责任公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-101558154-B | Phospholipases, nucleic acids encoding them, and methods of making and using them | DSM IP ASSETS B.V. (NL) | 2016-02-24 | — | — | CN | disclosed |
| CN-104450754-A | PHYTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP | 2015-03-25 | — | — | CN | disclosed |
| CN-102676158-B | Pyrene-contained bis-imidazole type fluorescence probe as well as synthetic method and application thereof | UNIV SHAANXI NORMAL | 2014-07-09 | — | — | CN | disclosed |
| CN-102676158-A | Pyrene-contained bis-imidazole type fluorescence probe as well as synthetic method and application thereof | UNIV SHAANXI NORMAL | 2012-09-19 | — | — | CN | disclosed |
| CN-101959882-A | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101558154-A | Phospholipases, nucleic acids encoding them, and methods of making and using them | VERENIUM CORP (US) | 2009-10-14 | — | — | CN | disclosed |
| CN-101541822-A | Phytases, nucleic acids encoding them and methods of making and using them | VERENIUM CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-101528766-A | Glucanases, nucleic acids encoding them and methods of making and using them | VERENIUM CORP (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-1233015-A1 | Use of imidazole derivatives for the treatement of deseases involving the AT1 and AT2s receptors of angiotensine, some of these products, their preparation, their application as medicaments and pharmaceutical compositions containing them | Aventis Pharma S.A. (FR) | 2002-08-21 | — | — | EP | disclosed |
| EP-0748314-B1 | TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THE SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AVENTIS PHARMA SA (FR) | 2002-05-15 | — | — | EP | disclosed |
| EP-0748315-A1 | USE OF IMIDAZOLE DERIVATIVES FOR TREATING DISORDERS INVOLVING ANGIOTENSIN RECEPTORS AT 1? AND AT 2?, CERTAIN SUCH PRODUCTS, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-12-18 | — | — | EP | disclosed |
| EP-0748314-A1 | NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023792-A1 | USE OF IMIDAZOLE DERIVATIVES FOR TREATING DISORDERS INVOLVING ANGIOTENSIN RECEPTORS AT1 AND AT2, CERTAIN SUCH PRODUCTS, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995023791-A1 | NOVEL TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, RESULTING NOVEL INTERMEDIATES, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1995-09-08 | — | — | WO | disclosed |