Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 19/20 | 0.84 |
| ▸ | EDNRB | P24530 | 18/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479736 | 0.96 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8311606 | 0.90 | EDNRB (0.67) | EDNRAEDNRB | |
| SCHEMBL5493621 | 0.86 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL7483156 | 0.84 | EDNRB (0.78) | EDNRAEDNRB | |
| SCHEMBL14289233 | 0.84 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL7479954 | 0.83 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL7483162 | 0.82 | EDNRB (0.74) | EDNRAEDNRB | |
| SCHEMBL14380540 | 0.81 | EDNRB (0.90) | EDNRAEDNRB | |
| SCHEMBL15257227 | 0.81 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL6780089 | 0.80 | EDNRA (0.85) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959072-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | claimed |
| EP-0959072-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1999-11-24 | — | — | EP | disclosed |
| EP-0743307-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |