Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31058600 | 0.95 | ALDH1A1 (0.33) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL30995058 | 0.86 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4309011 | 0.65 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL14485011 | 0.60 | — | — | |
| SCHEMBL4913305 | 0.60 | — | — | |
| SCHEMBL10638515 | 0.60 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10363679 | 0.59 | CRBN (0.33) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642871 | 0.57 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10260449 | 0.55 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642898 | 0.55 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-A1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000069846-A1 | 4,5,6,7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-11-23 | — | — | WO | disclosed |