Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473327 | 0.89 | DRD4 (0.57) | HPGDDRD4L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL7476376 | 0.88 | DRD4 (0.56) | HPGDDRD4L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL7470721 | 0.86 | DRD4 (0.56) | DRD4PKN1PKN2PARP1ADORA3 | |
| SCHEMBL312048 | 0.79 | TP53 (0.53) | HPGDALDH1A1MAPTPKN1PKN2 | |
| SCHEMBL6604643 | 0.79 | HPGD (0.63) | HPGDDRD4L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL6995989 | 0.78 | PKN1 (0.57) | HPGDDRD4ALDH1A1HSD17B10MAPT | |
| SCHEMBL7484755 | 0.77 | HPGD (0.57) | HPGDDRD4L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL7484204 | 0.75 | DRD4 (0.45) | DRD4ALDH1A1MAPTPKN1PKN2 | |
| SCHEMBL4888425 | 0.75 | PKN1 (0.55) | HPGDDRD4ALDH1A1HSD17B10MAPT | |
| SCHEMBL3947018 | 0.75 | PKN1 (0.55) | DRD4ALDH1A1MAPTKDM4EPKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |