Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480063 | 1.00 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7483007 | 1.00 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7480058 | 1.00 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL6583915 | 0.86 | HTR1A (0.45) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7481799 | 0.86 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7481855 | 0.86 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7481792 | 0.86 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7481862 | 0.86 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7479086 | 0.85 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7481888 | 0.85 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982305-B1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | claimed |
| US-6153625-A | Indan-1-ol compounds | ADIR ET COMPAGNIE (FR) | 2000-11-28 | — | — | US | claimed |
| EP-0982305-A1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-03-01 | — | — | EP | claimed |