Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7597564 | 0.99 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7966841 | 0.95 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7481524 | 0.94 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7963851 | 0.94 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7954262 | 0.93 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7973580 | 0.93 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7967198 | 0.93 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7474294 | 0.93 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7473089 | 0.93 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| SCHEMBL7480369 | 0.92 | MAP3K7 (0.36) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |