Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.33 |
| ▸ | TXK | P42681 | 1/20 | 0.33 |
| ▸ | BMX | P51813 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7962022 | 0.99 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7480849 | 0.94 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| Hydrochloric Acid SCHEMBL7481449 | 0.93 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7480376 | 0.93 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| Dimethylamine SCHEMBL7972125 | 0.93 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7964762 | 0.93 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7480014 | 0.92 | MAP3K7 (0.32) | IRAK4MAP3K7AURKAJAK2LCK | |
| Hydrochloric Acid SCHEMBL7597564 | 0.92 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7481684 | 0.92 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 | |
| SCHEMBL7962954 | 0.92 | AVPR2 (0.34) | AVPR2AVPR1AAVPR1BIRAK4MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |