Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 10/20 | 0.58 |
| ▸ | CACNA1D | Q01668 | 10/20 | 0.58 |
| ▸ | CACNA1S | Q13698 | 10/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421240 | 0.83 | MEN1 (0.76) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7266605 | 0.83 | MEN1 (0.76) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7272138 | 0.83 | MEN1 (0.76) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7480460 | 0.82 | CACNA1B (0.64) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| Hydrochloric Acid SCHEMBL7300438 | 0.82 | MEN1 (0.74) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7479482 | 0.80 | CACNA1B (0.65) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL3032197 | 0.80 | CACNA1F (0.71) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL3940339 | 0.80 | CACNA1F (0.71) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7266660 | 0.79 | CACNA1F (0.91) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7415057 | 0.79 | CACNA1F (0.91) | CACNA1BPDE1CCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779277-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-0779277-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORPORATION (JP) | 1997-06-18 | — | — | EP | disclosed |