Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7480772

CN(C1CCN(Cc2cccc(C(=N)N)c2)C1=O)S(=O)(=O)c1cc2ccccc2s1.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.56
F2 P00734 9/20 0.56
PRSS1 P07477 2/20 0.48
PROC P04070 2/20 0.48
PLAT P00750 1/20 0.48
PLG P00747 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7480777 1.00 F10 (0.56) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7568608 0.92 F10 (0.54) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7568609 0.92 F10 (0.54) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7479542 0.92 F10 (0.58) F10F2PLG
Trifluoroacetic Acid SCHEMBL7479535 0.92 F10 (0.58) F10F2PLG
Trifluoroacetic Acid SCHEMBL7565032 0.89 F10 (0.53) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7565038 0.89 F10 (0.53) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL8042826 0.88 F10 (0.56) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7481726 0.88 F10 (0.56) F10F2PRSS1PROCPLAT
Trifluoroacetic Acid SCHEMBL7486801 0.87 F10 (0.64) F10F2PRSS1PROCPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894088-A4 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2001-12-05 EP claimed
EP-0894088-A1 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-02-03 EP claimed
WO-1998024784-A1 SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-11 WO claimed
EP-0894088-A4 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2001-12-05 EP disclosed
US-6034093-A Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 2000-03-07 US disclosed
EP-0894088-A1 SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-02-03 EP disclosed
WO-1998024784-A1 SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-11 WO disclosed