Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8042826

CN([C@H]1CCN(Cc2csc(C(=N)N)c2)C1=O)S(=O)(=O)c1cc2ccccc2s1.O=C(O)C(F)(F)F

nearest known ligand 0.56

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.56
F2 P00734 11/20 0.56
PLAT P00750 2/20 0.56
PROC P04070 2/20 0.56
PLG P00747 1/20 0.56
KLK6 Q92876 3/20 0.47
PRSS1 P07477 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7481726 1.00 F10 (0.56) F10F2PLATPROCPLG
SCHEMBL7478953 0.94 F10 (0.62) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL7480777 0.88 F10 (0.56) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL7480772 0.88 F10 (0.56) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL8046765 0.87 F10 (0.53) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL8046768 0.87 F10 (0.53) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL8039973 0.84 F10 (0.55) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL8039972 0.84 F10 (0.55) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL2334198 0.82 F10 (0.74) F10F2PLATPROCPLG
Trifluoroacetic Acid SCHEMBL2329369 0.81 F10 (0.54) F10F2PLATPROCPLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034093-A Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 2000-03-07 US disclosed