Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632952 | 1.00 | DGAT1 (0.51) | DGAT1GPR183MIFCCNCCDK8 | |
| SCHEMBL22397868 | 1.00 | DGAT1 (0.51) | DGAT1GPR183MIFCCNCCDK8 | |
| SCHEMBL1469977 | 0.84 | MIF (0.67) | DGAT1GPR183MIFSMN1; SMN2CYP1A1 | |
| SCHEMBL1469976 | 0.84 | MIF (0.67) | DGAT1GPR183MIFSMN1; SMN2CYP1A1 | |
| SCHEMBL3170968 | 0.84 | DGAT1 (0.56) | DGAT1GPR183SMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6818301 | 0.83 | MIF (0.65) | DGAT1GPR183MIFSMN1; SMN2CYP1A1 | |
| SCHEMBL6818296 | 0.83 | GPR183 (0.49) | DGAT1GPR183MIFSMN1; SMN2CYP1A1 | |
| SCHEMBL1572450 | 0.83 | GPR183 (0.49) | DGAT1GPR183MIFSMN1; SMN2CYP1A1 | |
| SCHEMBL5751280 | 0.82 | CYP1A1 (0.55) | MIFPELI1CYP1A1CYP1B1 | |
| SCHEMBL5751272 | 0.82 | CYP1A1 (0.55) | MIFPELI1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222172-A1 | SYNTHESIS OF 1,3,5-TRISUBSTITUTED PYRAZOLES AND INTERMEDIATES THEREFORE | Bristol-Myers Squibb Pharma Company (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001029006-A1 | SYNTHESIS OF 1,3,5-TRISUBSTITUTED PYRAZOLES AND INTERMEDIATES THEREFORE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-04-26 | — | — | WO | disclosed |