Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.69 |
| ▸ | HTR1B | P28222 | 20/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HTR1F | P30939 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475892 | 0.88 | HTR1D (0.72) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7476719 | 0.85 | HTR1D (0.84) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL8899307 | 0.85 | HTR1D (0.71) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7473577 | 0.84 | HTR1D (0.73) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7480017 | 0.83 | HTR1D (0.68) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL8472304 | 0.81 | HTR1D (0.51) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7477505 | 0.80 | HTR1D (0.64) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7484414 | 0.80 | HTR1D (0.81) | HTR1DHTR1B | |
| SCHEMBL7476611 | 0.80 | HTR1D (0.71) | HTR1DHTR1BHTR2AHTR2CHTR1F | |
| SCHEMBL7483602 | 0.80 | HTR1D (0.87) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |