Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244012 | 0.96 | TSHR (0.61) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL7472992 | 0.92 | TSHR (0.53) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL7562061 | 0.87 | TSHR (0.43) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9656558 | 0.84 | KMT2A (0.44) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL7478103 | 0.81 | TSHR (0.67) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9043360 | 0.81 | TSHR (0.73) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9039574 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1MAOBGRIN2BS1PR1 | |
| SCHEMBL7476120 | 0.79 | TSHR (0.70) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9354355 | 0.79 | CYP2A13 (0.33) | TSHRKMT2AS1PR1S1PR5EPHX2 | |
| SCHEMBL6812792 | 0.77 | TSHR (0.58) | TSHRKMT2AGAAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-4921962-A | REACTION OF AMINE WITH HYDROPEROXIDE | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |