SCHEMBL9039574

SCHEMBL9039574

Cc1ccccc1CON1C(C)(C)CC(O)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
MMP1 P03956 4/20 0.39
ADAM17 P78536 2/20 0.39
MMP13 P45452 1/20 0.39
GBA1 P04062 2/20 0.38
S1PR1 P21453 1/20 0.36
S1PR5 Q9H228 1/20 0.36
CYP2A13 Q16696 1/20 0.36
MAOB P27338 1/20 0.35
EPHX2 P34913 1/20 0.35
ACHE P22303 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TACR1 P25103 2/20 0.34
GRIN2B Q13224 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354355 0.82 CYP2A13 (0.33) KMT2AMMP1ADAM17MMP13GBA1
SCHEMBL7562061 0.80 TSHR (0.43) KMT2AMMP1ADAM17MMP13S1PR1
SCHEMBL7480880 0.79 TSHR (0.56) KMT2AS1PR1S1PR5MAOBEPHX2
SCHEMBL9244012 0.79 TSHR (0.61) KMT2AS1PR1S1PR5MAOBALDH1A1
SCHEMBL7476946 0.78 SLC2A1 (0.35) KMT2AMMP1ADAM17MMP13CYP2A13
SCHEMBL7474629 0.78 KMT2A (0.41) KMT2ACYP2A13MAOBACHEADRA2A
SCHEMBL9240251 0.78 HTT (0.39) KMT2AMMP1ADAM17MMP13S1PR1
SCHEMBL9656558 0.78 KMT2A (0.44) KMT2AMMP1ADAM17MMP13S1PR1
SCHEMBL7472992 0.77 TSHR (0.53) KMT2AS1PR1S1PR5MAOBEPHX2
SCHEMBL7475382 0.76 SLC2A1 (0.38) S1PR1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389419-B1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA GEIGY AG (CH) 1996-05-01 EP claimed
US-5145893-A Photostability CIBA-GEIGY CORPORATION (US) 1992-09-08 US claimed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
US-5574162-A CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-11-12 US disclosed
EP-0389419-B1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA GEIGY AG (CH) 1996-05-01 EP disclosed
US-5442071-A Photostability CIBA-GEIGY CORPORATION (US) 1995-08-15 US disclosed
EP-0389430-B1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5359069-A Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-10-25 US disclosed
US-5286865-A Contain reactive functional group which can be chemically attached to selected polymer substrates CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
US-5145893-A Photostability CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
US-5021481-A For use with polymers CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed