Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.58 |
| ▸ | CTSL | P07711 | 5/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547062 | 0.88 | CACNA1B (0.57) | CACNA1BCTSLCTSKYAP1CTSS | |
| SCHEMBL7341833 | 0.86 | CACNA1B (0.62) | CACNA1BYAP1PTPN1PSMB11PSMA7 | |
| SCHEMBL7343211 | 0.85 | CACNA1B (0.59) | CACNA1BCTSLCTSKYAP1PTPN1 | |
| SCHEMBL7963499 | 0.85 | CACNA1B (0.61) | CACNA1BCTSLCTSKYAP1CTSS | |
| SCHEMBL7339830 | 0.84 | CACNA1B (0.68) | CACNA1BCTSLYAP1CTSSPSMB11 | |
| SCHEMBL7342880 | 0.84 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7342873 | 0.84 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7344934 | 0.84 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL21023244 | 0.84 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7344929 | 0.84 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | claimed |
| US-6362174-B1 | ANALGESICS, ANTIISCHEMIC AGENTS, ANTIEOILEPTIC AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |