Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.65 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.65 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961761 | 0.94 | PTGIR (0.61) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7479094 | 0.92 | PTGIR (0.73) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7949957 | 0.92 | PTGIR (0.73) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL9006885 | 0.92 | PTGIR (0.73) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7489473 | 0.91 | PTGER4 (0.64) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7490131 | 0.90 | PTGIR (0.69) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7495199 | 0.89 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7495210 | 0.89 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7990542 | 0.86 | PTGIR (0.76) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8066610 | 0.86 | PTGIR (0.72) | PTGIRPTGER4PTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437146-B1 | MESANGIAL PROLIFERATIVE GLOMERULONEPHRITIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| EP-1115712-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018744-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |