Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214641 | 0.91 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL6229260 | 0.81 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL576285 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6496032 | 0.80 | USP2 (0.39) | ALDH1A1 | |
| SCHEMBL4662102 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6213221 | 0.76 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL14779809 | 0.74 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL25486668 | 0.74 | TSHR (0.42) | — | |
| SCHEMBL25203219 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL15125809 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935601-A4 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARM CO (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-0935601-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | Du Pont Pharmaceuticals Company (US) | 1999-08-18 | — | — | EP | disclosed |
| WO-1997035539-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |