Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479701 | 0.92 | KMT2A (0.69) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7478655 | 0.87 | MAPT (0.58) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7478733 | 0.87 | ALDH1A1 (0.70) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7478023 | 0.86 | KDM4E (0.63) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7475994 | 0.86 | KDM4E (0.69) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7476908 | 0.86 | MAPT (0.60) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7479676 | 0.85 | KDM4E (0.65) | MAPTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7482747 | 0.85 | KMT2A (0.61) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7473340 | 0.84 | MAPT (0.60) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7472532 | 0.83 | KDM4E (0.63) | MAPTKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |