Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.65 |
| ▸ | F2 | P00734 | 5/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479772 | 0.91 | F10 (0.61) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7476336 | 0.91 | F10 (0.66) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7475336 | 0.88 | F10 (0.63) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7472782 | 0.85 | F10 (0.57) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7476586 | 0.82 | F10 (0.57) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7484805 | 0.79 | F10 (1.00) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7690926 | 0.78 | F10 (0.64) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7690925 | 0.78 | F10 (0.64) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7482436 | 0.77 | F10 (0.57) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL4352253 | 0.76 | F10 (1.00) | F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |