SCHEMBL748231

SCHEMBL748231

CN1CC(=O)N2[C@@H](CCS(C)(=O)=O)C(=O)N(Cc3ccc(F)cc3F)C[C@@H]2N1C(=O)NCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CLPP Q16740 3/20 0.43
CYP3A4 P08684 17/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10224764 0.91 CLPP (0.46) CLPPCYP3A4
SCHEMBL762979 0.90 CLPP (0.45) CLPPCYP3A4
SCHEMBL747595 0.90 CLPP (0.44) CLPPCYP3A4
SCHEMBL748815 0.90 CLPP (0.52) CLPPCYP3A4
SCHEMBL10224763 0.89 CLPP (0.56) CLPPCYP3A4
SCHEMBL10224765 0.89 CLPP (0.44) CLPPCYP3A4
SCHEMBL14620213 0.88 CLPP (0.43) CLPPCYP3A4
SCHEMBL747342 0.88 CLPP (0.51) CLPPCYP3A4
SCHEMBL744821 0.87 CLPP (0.55) CLPPCYP3A4
SCHEMBL749277 0.87 CLPP (0.41) CLPPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138337-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2012-03-20 US disclosed
US-8138337-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2012-03-20 US disclosed
US-7932384-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2011-04-26 US disclosed
US-7671054-B1 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2010-03-02 US disclosed
US-7671054-B1 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2010-03-02 US disclosed
US-7566711-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2009-07-28 US disclosed
US-7566711-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2009-07-28 US disclosed