Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.54 |
| ▸ | PPARA | Q07869 | 13/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481024 | 0.90 | FFAR1 (0.50) | PPARGPPARAFFAR1 | |
| SCHEMBL9128417 | 0.86 | FFAR1 (0.67) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL13960286 | 0.85 | KDM4E (0.55) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL14373654 | 0.83 | KDM4E (0.59) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL7491201 | 0.83 | FFAR1 (0.53) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL9128422 | 0.82 | PPARG (0.53) | PPARGPPARAKDM4E | |
| SCHEMBL7879558 | 0.81 | KDM4E (0.56) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL7481609 | 0.81 | FFAR1 (0.47) | PPARGPPARAFFAR1 | |
| SCHEMBL7489196 | 0.80 | FFAR1 (0.50) | PPARGPPARAFFAR1KDM4E | |
| SCHEMBL6387754 | 0.80 | PPARG (0.77) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643050-B1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5614544-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |