SCHEMBL7483791

SCHEMBL7483791

CCOc1cc(N(CC)CC)ccc1C1(c2ccc(N(CC)c3ccccc3)cc2OCC)OC(=O)c2cccnc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
ALDH1A1 P00352 3/20 0.33
RPS6KA2 Q15349 1/20 0.33
MAPT P10636 7/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 2/20 0.33
RAB9A P51151 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
PDE5A O76074 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
RXRA P19793 2/20 0.32
RXRB P28702 2/20 0.32
RXRG P48443 2/20 0.32
NR3C2 P08235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30444451 0.92 CYP3A4 (0.42) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL28284 0.92 CYP3A4 (0.42) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL29430021 0.92 CYP3A4 (0.42) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL9183030 0.89 CYP3A4 (0.39) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL11967217 0.89 CYP3A4 (0.39) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL9186497 0.89 ALDH1A1 (0.41) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL20383174 0.88 CYP3A4 (0.39) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL9255478 0.87 CYP3A4 (0.39) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL19869604 0.86 CYP3A4 (0.37) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A
SCHEMBL9184678 0.85 CYP3A4 (0.39) CYP3A4ALDH1A1RPS6KA2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664292-B1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS INC (JP) 2002-06-19 EP disclosed
US-5627287-A COLORLESS YAMAMOTO CHEMICALS, INC. (JP) 1997-05-06 US disclosed
EP-0664292-A1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS, INC. (JP) 1995-07-26 EP disclosed