Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487808 | 0.90 | PTGS2 (0.49) | PTGS2GPR17MCL1 | |
| SCHEMBL7484432 | 0.86 | PTGS2 (0.48) | PTGS2GPR17MCL1 | |
| SCHEMBL7479480 | 0.82 | PTGS2 (0.43) | PTGS2GPR17MCL1 | |
| SCHEMBL6171586 | 0.82 | PTGS2 (0.64) | PTGS2GPR17 | |
| SCHEMBL7482841 | 0.82 | PTGS2 (0.47) | PTGS2GPR17 | |
| SCHEMBL7482284 | 0.82 | PTGS2 (0.48) | PTGS2GPR17MCL1 | |
| SCHEMBL7478044 | 0.81 | MCL1 (0.38) | PTGS2MCL1 | |
| SCHEMBL7487942 | 0.80 | GPR17 (0.43) | PTGS2GPR17 | |
| SCHEMBL27532332 | 0.79 | PTGS2 (0.53) | PTGS2MCL1 | |
| SCHEMBL7485576 | 0.79 | PTGS2 (0.42) | PTGS2GPR17MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | claimed |
| EP-1065206-A1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER INC. (US) | 2001-01-03 | — | — | EP | claimed |
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1065206-A1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER INC. (US) | 2001-01-03 | — | — | EP | disclosed |