Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939398 | 0.89 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6942791 | 0.89 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6939312 | 0.80 | MAPT (0.59) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6939305 | 0.80 | MAPT (0.59) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6941788 | 0.80 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6943858 | 0.80 | MAPT (0.58) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6941011 | 0.80 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6939693 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6943333 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTHPGDTDP1 | |
| SCHEMBL6939699 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | claimed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | claimed |
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |