SCHEMBL748421

SCHEMBL748421

CCn1nc(C(F)F)c(C=O)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955890 0.88
SCHEMBL29953441 0.87
SCHEMBL29954017 0.84
SCHEMBL15330240 0.84 KMT2A (0.32)
SCHEMBL28461548 0.83
SCHEMBL29110089 0.82
SCHEMBL29110091 0.82
SCHEMBL15331915 0.81 HTR2C (0.32)
SCHEMBL19393130 0.81
SCHEMBL15332614 0.80 ADRA1A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943900-B Isoxazoline derivatives and their use in agriculture 宁夏苏融达化工有限公司 2023-11-17 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-112794846-B Ethyl isoxazoline derivative and application thereof 宁夏苏融达化工有限公司 2022-09-20 CN disclosed
CN-111574509-B Isoxazoline derivatives and their use in agriculture 宁夏苏融达化工有限公司 2021-08-31 CN disclosed
CN-112794846-A Ethyl isoxazoline derivative and application thereof 东莞市东阳光农药研发有限公司 2021-05-14 CN disclosed
CN-111943900-A Isoxazoline derivatives and their use in agriculture 东莞市东阳光农药研发有限公司 2020-11-17 CN disclosed
CN-110511216-B Isoxazoline derivatives and their use in agriculture 东莞市东阳光农药研发有限公司 2020-09-11 CN disclosed
CN-111574509-A Isoxazoline derivatives and their use in agriculture 东莞市东阳光农药研发有限公司 2020-08-25 CN disclosed
CN-110511216-A Isoxazoline derivative and its application in agricultural DONGGUAN DONGYANGGUANG PESTICIDE RES AND DEVELOPMENT CO LTD 2019-11-29 CN disclosed
EP-2430000-A2 FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2012-03-21 EP disclosed
WO-2010130767-A2 FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-11-18 WO disclosed