Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.44 |
| ▸ | RXRA | P19793 | 4/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487529 | 0.94 | NR4A2 (0.43) | NR4A2RXRANR4A1NR4A3PTGIR | |
| SCHEMBL7493134 | 0.89 | NR4A2 (0.41) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7491988 | 0.88 | NR4A2 (0.41) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7496987 | 0.87 | NR4A2 (0.49) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7490736 | 0.87 | NR4A2 (0.41) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7493526 | 0.86 | NR4A2 (0.45) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7493599 | 0.86 | NR4A2 (0.51) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7481949 | 0.84 | NR4A2 (0.46) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7492835 | 0.84 | PTGIR (0.44) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL7489527 | 0.82 | PTGIR (0.51) | NR4A2NR4A1NR4A3PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |