Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 12/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498928 | 0.88 | PTGIR (0.45) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7484361 | 0.88 | NR4A2 (0.44) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7493134 | 0.86 | NR4A2 (0.41) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7490736 | 0.84 | NR4A2 (0.41) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7491313 | 0.84 | PTGIR (0.43) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7493526 | 0.84 | NR4A2 (0.45) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7481949 | 0.83 | NR4A2 (0.46) | NR4A2RXRARXRBPTGIRNR4A1 | |
| SCHEMBL7487529 | 0.82 | NR4A2 (0.43) | NR4A2RXRAPTGIRNR4A1NR4A3 | |
| SCHEMBL7481647 | 0.77 | NR4A2 (0.42) | NR4A2RXRAMEN1CYP1A2HTR1A | |
| SCHEMBL7493599 | 0.76 | NR4A2 (0.51) | NR4A2RXRARXRBNR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |