Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FURIN | P09958 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475225 | 0.90 | F10 (1.00) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7475473 | 0.90 | F10 (1.00) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7471700 | 0.89 | F10 (1.00) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7476367 | 0.87 | F10 (0.83) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7479884 | 0.87 | F10 (1.00) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7477445 | 0.83 | F10 (0.71) | F10PRSS1LMNAMAPTHTT | |
| SCHEMBL7475462 | 0.83 | F10 (0.81) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7479235 | 0.79 | F10 (0.70) | F10PRSS1LMNAALDH1A1MAPT | |
| SCHEMBL7484460 | 0.77 | F10 (0.62) | F10PRSS1LMNAMAPTMEN1 | |
| SCHEMBL5165467 | 0.75 | F10 (0.68) | F10PRSS1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |