SCHEMBL748456

SCHEMBL748456

CC(=O)NCCC(=O)NCCc1c[nH]cn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 1/20 0.42
QPCTL Q9NXS2 1/20 0.42
MTNR1A P48039 6/20 0.39
MTNR1B P49286 5/20 0.36
KDM4E B2RXH2 3/20 0.36
F13A1 P00488 1/20 0.36
ACACB O00763 1/20 0.36
LMNA P02545 3/20 0.36
BLM P54132 3/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP1A2 P05177 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514228 0.91 QPCT (0.49) QPCTQPCTLMTNR1AMTNR1BKDM4E
SCHEMBL17473827 0.88 CYP3A4 (0.41) LMNATSHRCYP2C19CYP3A4CYP2D6
SCHEMBL7776365 0.85 HPGD (0.47) MTNR1AMTNR1BTSHRALDH1A1HPGD
SCHEMBL17473832 0.85 HDAC3 (0.41) MTNR1AMTNR1BF13A1LMNATSHR
SCHEMBL17473829 0.85 HDAC3 (0.42) MTNR1ALMNATSHRCYP2C19CYP3A4
SCHEMBL17473828 0.83 ST14 (0.36) QPCTQPCTLLMNATSHRCYP2C19
SCHEMBL8649260 0.83 CA1 (0.45) KDM4ECYP3A4HTTALDH1A1NPSR1
Carcinine SCHEMBL2819350 0.82 CYP3A4 (0.54) LMNATSHRCYP2C19CYP3A4CYP2D6
SCHEMBL14232911 0.82 SMN1; SMN2 (0.43) MTNR1AMTNR1BKDM4EACACBTSHR
SCHEMBL7758880 0.82 TSHR (0.35) MTNR1ALMNATSHRCYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10406383-B2 Apparatus for treatment of dermatological conditions CAREWEAR CORP. (US) 2019-09-10 US claimed
EP-2431075-B1 Apparatus for treatment of dermatological conditions SONOVIA HOLDINGS LLC (US) 2017-04-05 EP claimed
EP-0684944-B1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL SA (MC) 2001-07-25 EP claimed
EP-0684944-A1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL S.A.M. (MC) 1995-12-06 EP claimed
WO-1994019325-A1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) 1994-09-01 WO claimed
US-12059370-B2 Flexible skin therapy device having phosphorus material with light and transparent electrical stimulation layers CAREWEAR CORP. 2024-08-13 US disclosed
EP-3446742-B1 LIGHT THERAPY DEVICE CAREWEAR CORP (US) 2023-06-21 EP disclosed
US-11083619-B2 Organic LED light and ultrasonic transducer device in a flexible layer configuration with electrical stimulation CAREWEAR CORP. (US) 2021-08-10 US disclosed
EP-3446743-B1 ULTRASONIC TRANSDUCER DEVICE CAREWEAR CORP (US) 2020-10-14 EP disclosed
US-10406383-B2 Apparatus for treatment of dermatological conditions CAREWEAR CORP. (US) 2019-09-10 US disclosed
US-20190151655-A1 LIGHT AND ULTRASONIC TRANSDUCER DEVICE CAREWEAR CORP. (US) 2019-05-23 US disclosed
EP-2968883-B1 LIGHT AND ULTRASONIC TRANSDUCER DEVICE CAREWEAR CORP (US) 2018-10-10 EP disclosed
US-20120259252-A1 Coupling Emulsions for Use With Ultrasound Devices AVON PRODUCTS, INC. (US) 2012-10-11 US disclosed
EP-2431075-A1 Apparatus for treatment of dermatological conditions Sonovia Limited (GB) 2012-03-21 EP disclosed
US-20110269693-A1 Apparatus for treatment of dermatological conditions DERMAGLAIA LTD. (GB) 2011-11-03 US disclosed
US-20080051680-A1 Apparatus for Treatment of Dermatological Conditions SONOVIA HOLDINGS LLC 2008-02-28 US disclosed
EP-0684944-B1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL SA (MC) 2001-07-25 EP disclosed
US-5792784-A A PSEUDO-DIPEPTIDE PRODUCT WHICH IS HISTAMINE OR METHYL-SUBSTITUTED HISTAMINE COUPLED WITH A AMINO ACID; USED IN THERAPEUTICAL, COSMETOLOGICAL APPLICATIONS AND TREATS VISION DEFECT Babizhayev, Marc (SU) 1998-08-11 US disclosed
EP-0684944-A1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL S.A.M. (MC) 1995-12-06 EP disclosed
WO-1994019325-A1 COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) 1994-09-01 WO disclosed