SCHEMBL514228

SCHEMBL514228

CC(=O)NCCc1c[nH]cn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 1/20 0.49
QPCTL Q9NXS2 1/20 0.49
MTNR1A P48039 10/20 0.44
KDM4E B2RXH2 3/20 0.42
F13A1 P00488 1/20 0.42
BLM P54132 3/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 2/20 0.41
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
MTNR1B P49286 9/20 0.41
ACACB O00763 1/20 0.41
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL748456 0.91 QPCT (0.42) QPCTQPCTLMTNR1AKDM4EF13A1
SCHEMBL21820172 0.86 CNR1 (0.36) QPCTQPCTLMTNR1AMEN1TSHR
SCHEMBL17473831 0.86 MMP9 (0.35) QPCTQPCTLMTNR1AKDM4ECYP1A2
SCHEMBL8612877 0.85 MAPK1 (0.36) QPCTQPCTLMTNR1ABLMLMNA
SCHEMBL17038779 0.85 MTNR1B (0.42) QPCTQPCTLMTNR1ACYP1A2KMT2A
SCHEMBL13734799 0.84 MAPT (0.33) QPCTQPCTLMTNR1AMEN1KMT2A
SCHEMBL17473828 0.84 ST14 (0.36) QPCTQPCTLLMNAMEN1PKM
SCHEMBL14232911 0.83 SMN1; SMN2 (0.43) MTNR1AKDM4EMEN1TSHRKMT2A
SCHEMBL8226307 0.83 QPCT (0.33) QPCTQPCTLMTNR1AKDM4EF13A1
SCHEMBL7631284 0.83 MTNR1A (0.40) QPCTQPCTLMTNR1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
WO-2025123045-A1 PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-06-12 WO claimed
CN-119555822-A Urine metabolism marker composition for diagnosis of cancer seeds of pan-cancer, screening method and application 哈尔滨脉图精准技术有限公司 2025-03-04 CN claimed
CN-119324053-A Model and index for evaluating aging delaying effect of estrogen replacement therapy and application of model and index 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-17 CN claimed
US-20240400468-A1 Bionutritional Compositions for Plants and Soils ENVIROKURE, INCORPORATED (US) 2024-12-05 US claimed
EP-4377280-A1 BIONUTRITIONAL COMPOSITIONS FOR PLANTS AND SOILS Envirokure Incorporated (US) 2024-06-05 EP claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
CN-115862762-A Method for predicting ionization efficiency of mass spectrum of compound based on quantitative structure-activity relationship model of COSMO-RS (least squares) and ANN (artificial neural network) algorithm 大连工业大学 2023-03-28 CN claimed
WO-2023009636-A1 BIONUTRITIONAL COMPOSITIONS FOR PLANTS AND SOILS ENVIROKURE, INCORPORATED (US) 2023-02-02 WO claimed
CN-114720615-A Pancreatic cancer early diagnosis marker and tissue screening method and application thereof 上海市第一人民医院 2022-07-08 CN claimed
EP-3766959-A1 FECAL STORAGE METHOD Metabologenomics, Inc. (JP) 2021-01-20 EP claimed
US-10603296-B1 Compositions and methods for diagnosis and treatment of neuromuscular disorders UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-03-31 US claimed
WO-2019177166-A1 FECAL STORAGE METHOD 株式会社メタジェン 2019-09-19 WO claimed
US-20180318260-A1 COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSIS THE SCRIPPS RESEARCH INSTITUTE 2018-11-08 US claimed
CN-105765383-B Cancer of pancreas is with saliva biomarker and has used diagnostic method of the cancer of pancreas with the cancer of pancreas of saliva biomarker 唾液科技有限公司 2018-04-10 CN claimed
WO-2017079547-A2 COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSIS THE SCRIPPS RESEARCH INSTITUTE (US) 2017-05-11 WO claimed
US-20160282351-A1 SALIVARY BIOMARKERS FOR CANCERS, METHODS AND DEVICES FOR ASSAYING THE SAME, AND METHODS FOR DETERMINING SALIVARY BIOMARKERS FOR CANCERS SALIVATECH CO., LTD. (JP) 2016-09-29 US claimed
EP-3064940-A1 SALIVARY BIOMARKER FOR CANCER, METHOD AND DEVICE FOR ASSAYING SAME, AND METHOD FOR DETERMINING SALIVARY BIOMARKER FOR CANCER Salivatech Co., Ltd. (JP) 2016-09-07 EP claimed
CN-105765383-A SALIVARY BIOMARKER FOR CANCER, METHOD AND DEVICE FOR ASSAYING SAME, AND METHOD FOR DETERMINING SALIVARY BIOMARKER FOR CANCER 唾液科技有限公司 2016-07-13 CN claimed
CN-1053233-C Agent for surface processing of copper and copper alloy MIKO CO LTD (JP) 2000-06-07 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 QPCT 1830/4885QPCTL 1024/4885MTNR1A 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.