Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490311 | 0.89 | HRH3 (0.42) | HRH3HCRTR1HCRTR2SLC6A4SCD5 | |
| SCHEMBL7490301 | 0.89 | HRH3 (0.42) | HRH3HCRTR1HCRTR2SLC6A4SCD5 | |
| SCHEMBL7485078 | 0.79 | HRH3 (0.58) | HRH3 | |
| SCHEMBL7494540 | 0.76 | HRH3 (0.43) | HRH3HCRTR1HCRTR2KDM2BSLC6A4 | |
| SCHEMBL7445185 | 0.75 | SLC6A4 (0.39) | HRH3HCRTR1HCRTR2SLC6A4DPP4 | |
| SCHEMBL7488107 | 0.74 | DPP4 (0.39) | HRH3KDM2BSCD5SCDDPP4 | |
| SCHEMBL7441337 | 0.74 | DRD2 (0.46) | HRH3HCRTR1HCRTR2KDM2BSLC6A4 | |
| SCHEMBL7494232 | 0.74 | HRH3 (0.46) | HRH3HCRTR1HCRTR2KDM2B | |
| SCHEMBL7485138 | 0.74 | HRH3 (0.41) | HRH3HCRTR1HCRTR2KDM2BSLC6A4 | |
| SCHEMBL7485307 | 0.73 | HRH3 (0.43) | HRH3HCRTR1HCRTR2KDM2BDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |