Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 2/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.49 |
| ▸ | CLPP | Q16740 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748672 | 0.92 | CYP3A4 (0.56) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL749259 | 0.90 | CTNNB1 (0.60) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL747815 | 0.87 | CYP3A4 (0.56) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL748099 | 0.86 | CYP3A4 (0.56) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL13344277 | 0.86 | CYP3A4 (0.57) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL748379 | 0.85 | CLPP (0.63) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL14620313 | 0.84 | CTNNB1 (0.52) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL3655743 | 0.83 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL10291397 | 0.83 | CTNNB1 (0.52) | TCF4CTNNB1CREBBPCYP3A4CLPP | |
| SCHEMBL10227148 | 0.83 | CYP3A4 (0.56) | TCF4CTNNB1CREBBPCYP3A4CLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138337-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-03-20 | — | — | US | disclosed |
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |