Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484772 | 0.92 | PTGS2 (0.52) | PTGS2PTGS1MCL1 | |
| SCHEMBL7484382 | 0.92 | PTGS2 (0.68) | PTGS2PTGS1EGFR | |
| SCHEMBL7481159 | 0.90 | PTGS2 (0.52) | PTGS2PTGS1MCL1 | |
| SCHEMBL7482305 | 0.86 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7479173 | 0.86 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7486073 | 0.84 | PTGS2 (0.58) | PTGS2PTGS1EGFR | |
| SCHEMBL7482841 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL7480098 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7484432 | 0.81 | PTGS2 (0.48) | PTGS2PTGS1MCL1 | |
| SCHEMBL7484972 | 0.80 | PTGS2 (0.51) | PTGS2PTGS1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | claimed |
| EP-1065206-A1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER INC. (US) | 2001-01-03 | — | — | EP | claimed |
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1065206-A1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER INC. (US) | 2001-01-03 | — | — | EP | disclosed |