Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | RGS12 | O14924 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TERT | O14746 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075775 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL13176359 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL12132257 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL822756 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL14156552 | 0.96 | MEN1 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL13259600 | 0.95 | MEN1 (0.59) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL13259581 | 0.95 | MEN1 (0.59) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL284967 | 0.93 | STAT3 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL1105114 | 0.93 | STAT3 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A | |
| SCHEMBL7485132 | 0.93 | STAT3 (0.65) | ALDH1A1MEN1RGS12HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141140-B1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | CIBA SC HOLDING AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| EP-1141140-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | Ciba SC Holding AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| US-6143890-A | Naphthalenehydrazamimides and perylenehydrazamimides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| WO-2000040657-A1 | NAPHTHALENEHYDRAZAMIMIDES AND PERYLENEHYDRAZAMIMIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-13 | — | — | WO | disclosed |