Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100505 | 0.81 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL1376798 | 0.80 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7482337 | 0.79 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL1377386 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7606499 | 0.72 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL1379215 | 0.71 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL1376884 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7844081 | 0.68 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6580476 | 0.67 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL5097621 | 0.67 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263751-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2002-12-11 | — | — | EP | claimed |
| WO-2001068633-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2001-09-20 | — | — | WO | claimed |