Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991135 | 0.83 | MAOB (0.50) | MAOBIDO1KMT2AMAOAPTPN1 | |
| SCHEMBL16399837 | 0.72 | MAOB (0.46) | MAOBIDO1HRH3KMT2AMAOA | |
| SCHEMBL5024279 | 0.65 | IDO1 (0.63) | MAOBIDO1HRH3KMT2AMAOA | |
| SCHEMBL17520335 | 0.65 | IDO1 (0.63) | MAOBIDO1KMT2A | |
| SCHEMBL492736 | 0.64 | IDO1 (0.68) | MAOBIDO1KMT2APTPN1 | |
| SCHEMBL3965409 | 0.64 | LTA4H (0.36) | MAOB | |
| SCHEMBL2873573 | 0.63 | MAOB (0.69) | MAOBIDO1HRH3PTPN1 | |
| SCHEMBL15977186 | 0.63 | MAOB (0.43) | MAOBIDO1HRH3KMT2AMAOA | |
| SCHEMBL4883457 | 0.62 | MAOB (0.72) | MAOBPTPN1 | |
| Ammonia Solution, Strong SCHEMBL6903652 | 0.62 | MAOB (0.67) | MAOBIDO1HRH3MAOAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087851-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIMIDINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |