Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898031 | 1.00 | ADAM17 (0.63) | ADAM17MMP2 | |
| SCHEMBL5897887 | 0.93 | ADAM17 (0.57) | ADAM17MMP2 | |
| SCHEMBL5897955 | 0.93 | ADAM17 (0.61) | ADAM17MMP2 | |
| SCHEMBL5898335 | 0.90 | ADAM17 (0.61) | ADAM17MMP2 | |
| SCHEMBL5898245 | 0.90 | ADAM17 (0.57) | ADAM17MMP2 | |
| Trifluoroacetic Acid SCHEMBL7486132 | 0.90 | ADAM17 (0.74) | ADAM17MMP2 | |
| Trifluoroacetic Acid SCHEMBL5898025 | 0.90 | ADAM17 (0.74) | ADAM17MMP2 | |
| SCHEMBL5898033 | 0.88 | ADAM17 (0.80) | ADAM17MMP2 | |
| SCHEMBL7493170 | 0.88 | ADAM17 (0.80) | ADAM17MMP2 | |
| SCHEMBL5898039 | 0.86 | ADAM17 (0.60) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263755-A2 | CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | Bristol-Myers Squibb Pharma Company (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001070673-A2 | CYCLIC β-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-$g(a) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |