Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837367 | 0.84 | AHR (0.44) | HTR5AHTT | |
| SCHEMBL7483478 | 0.83 | HTR5A (0.39) | HTR5AHDAC3ACHEKMT2A | |
| SCHEMBL7833042 | 0.82 | PDE3B (0.47) | DDB1CRBNACHEPDE3BPDE3A | |
| SCHEMBL7836971 | 0.80 | CREBBP (0.46) | HTR5ADDB1CRBN | |
| SCHEMBL7826445 | 0.76 | CA9 (0.43) | HTR5ADDB1CRBNKMT2A | |
| SCHEMBL7825601 | 0.76 | CMA1 (0.44) | HTR5AHTT | |
| SCHEMBL4622546 | 0.74 | HTR5A (0.43) | HTR5AACHEPDE3BPDE3A | |
| SCHEMBL13878894 | 0.72 | HTR5A (0.45) | HTR5AHDAC3ACHEKMT2A | |
| SCHEMBL31552579 | 0.72 | HTR5A (0.45) | HTR5AHDAC3ACHEKMT2A | |
| Hydrochloric Acid SCHEMBL4072833 | 0.71 | HTR5A (0.44) | HTR5AHDAC3ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |