Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452780 | 1.00 | SCN7A (0.38) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7485841 | 0.99 | SLC6A4 (0.38) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7452435 | 0.99 | SLC6A4 (0.38) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7490459 | 0.89 | HRH3 (0.37) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7536239 | 0.89 | RORC (0.39) | SLC6A4TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7536225 | 0.89 | RORC (0.39) | SLC6A4TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7490466 | 0.89 | HRH3 (0.37) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7491392 | 0.88 | SLC6A4 (0.42) | SCN7AKCNH2SLC6A4TSHRKDM4E | |
| SCHEMBL7447108 | 0.86 | MEN1 (0.39) | SLC6A4HRH3KMT2A | |
| SCHEMBL7490293 | 0.86 | DPP4 (0.44) | SLC6A4TSHRKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |