Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | UTRN | P46939 | 7/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486298 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7481916 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7481919 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7481914 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7486231 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7482815 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7486239 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7482810 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL7482819 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL6965542 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1CYP1A2SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643050-B1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5614544-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0643050-A1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |