Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.81 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146545 | 0.90 | TAAR1 (1.00) | TAAR1MAOBLOXL2DRD2DRD1 | |
| SCHEMBL29429505 | 0.90 | TAAR1 (1.00) | TAAR1MAOBLOXL2DRD2DRD1 | |
| Iodide SCHEMBL30472769 | 0.88 | TAAR1 (0.96) | TAAR1MAOBLOXL2DRD2DRD1 | |
| Iodide SCHEMBL29040442 | 0.88 | TAAR1 (0.96) | TAAR1MAOBLOXL2DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL5728333 | 0.88 | TAAR1 (0.96) | TAAR1MAOBLOXL2DRD2DRD1 | |
| Bromide SCHEMBL30599495 | 0.88 | TAAR1 (0.96) | TAAR1MAOBLOXL2DRD2DRD1 | |
| Bromide SCHEMBL28591635 | 0.88 | TAAR1 (0.96) | TAAR1MAOBLOXL2DRD2DRD1 | |
| SCHEMBL28812860 | 0.86 | TAAR1 (0.70) | TAAR1MAOBLOXL2DRD2IDO1 | |
| SCHEMBL5790976 | 0.84 | TAAR1 (0.67) | TAAR1MAOBLOXL2IDO1AGXT | |
| SCHEMBL28579791 | 0.83 | TAAR1 (0.85) | TAAR1MAOBLOXL2DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218384-A4 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1218384-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023392-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | disclosed |