SCHEMBL146545

SCHEMBL146545

NCCc1cccc(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 12/20 1.00
MAOB P27338 2/20 0.64
DRD2 P14416 1/20 0.57
DRD1 P21728 1/20 0.57
IDO1 P14902 2/20 0.55
AGXT P21549 2/20 0.55
CYP2A6 P11509 1/20 0.52
HTR2A P28223 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HTR2C P28335 1/20 0.50
HTR6 P50406 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429505 1.00 TAAR1 (1.00) TAAR1MAOBDRD2DRD1IDO1
Iodide SCHEMBL29040442 0.98 TAAR1 (0.96) TAAR1MAOBDRD2DRD1IDO1
Iodide SCHEMBL30472769 0.98 TAAR1 (0.96) TAAR1MAOBDRD2DRD1IDO1
Bromide SCHEMBL30599495 0.98 TAAR1 (0.96) TAAR1MAOBDRD2DRD1IDO1
Hydrochloric Acid SCHEMBL5728333 0.98 TAAR1 (0.96) TAAR1MAOBDRD2DRD1IDO1
Bromide SCHEMBL28591635 0.98 TAAR1 (0.96) TAAR1MAOBDRD2DRD1IDO1
SCHEMBL30568761 0.92 TAAR1 (0.85) TAAR1MAOBDRD2DRD1IDO1
SCHEMBL28579791 0.92 TAAR1 (0.85) TAAR1MAOBDRD2DRD1IDO1
SCHEMBL7486349 0.90 TAAR1 (0.81) TAAR1MAOBDRD2DRD1IDO1
SCHEMBL1317595 0.87 TAAR1 (0.77) TAAR1MAOBDRD2IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2026-01-08 US claimed
WO-2025137551-A1 AMINE PURIFICATION IN A CARBON CAPTURE METHOD USING MOF BODIES SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2025-06-26 WO claimed
CN-114420852-B Preparation method of pure-phase RP perovskite film 河北工业大学 2025-05-27 CN claimed
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-120018406-A Fine circuit pattern diffusion inhibitor and preparation method and application method thereof 深圳市板明科技股份有限公司 2025-05-16 CN claimed
CN-119726347-A Non-external-cavity near-infrared perovskite laser and preparation method thereof 中国科学院半导体研究所 2025-03-28 CN claimed
CN-119726348-A Near-infrared perovskite laser and preparation method thereof 中国科学院半导体研究所 2025-03-28 CN claimed
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-119371337-A Metal halide perovskite nanocrystalline resistant to heat-induced fluorescence quenching, and preparation method and application thereof 华南理工大学 2025-01-28 CN claimed
WO-2002006229-A2 HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS WYETH (US) 2002-01-24 WO claimed
EP-1155001-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2001-11-21 EP claimed
EP-1142877-A1 2-OXOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF JAPAN TOBACCO INC. (JP) 2001-10-10 EP claimed
WO-2001023392-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-05 WO claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION NOS2, DUOX2, SMOX TAAR1 660/4885MAOB 462/4885DRD2 777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.