Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488760 | 0.84 | AHR (0.57) | AHRATMMEN1KMT2AMAPK1 | |
| SCHEMBL23470239 | 0.83 | KDM4E (0.62) | AHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9410535 | 0.80 | HSD11B1 (0.57) | AHRALDH1A1KDM4EGAAHSD11B1 | |
| SCHEMBL1809674 | 0.78 | AHR (0.57) | AHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1810369 | 0.77 | AHR (0.56) | AHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12188773 | 0.76 | KDM4E (0.45) | AHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL986506 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL15101474 | 0.74 | MAPK1 (0.75) | ALDH1A1MEN1KMT2AMAPK1TSHR | |
| SCHEMBL14995866 | 0.73 | AHR (0.46) | AHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31264288 | 0.73 | AHR (0.76) | AHRATMMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |