Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 4/20 | 0.33 |
| ▸ | PLAU | P00749 | 4/20 | 0.33 |
| ▸ | PLAT | P00750 | 3/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483993 | 0.93 | F10 (0.47) | F2F10PLGPLAUPLAT | |
| SCHEMBL7491010 | 0.89 | F2 (0.42) | F2F10EGFRPLGPLAU | |
| SCHEMBL7422372 | 0.88 | F2 (0.46) | F2F10EGFRPLGPLAU | |
| SCHEMBL7485110 | 0.87 | F10 (0.47) | F2F10PLGPLAUPLAT | |
| SCHEMBL7496461 | 0.87 | F2 (0.47) | F2F10EGFRPLGPLAU | |
| SCHEMBL7488289 | 0.87 | F2 (0.43) | F2F10PLGPLAUPLAT | |
| SCHEMBL7415526 | 0.85 | F2 (0.52) | F2F10EGFRPTGER1CCR8 | |
| SCHEMBL7415749 | 0.85 | F2 (0.53) | F2F10EGFRPLGPLAU | |
| SCHEMBL7487939 | 0.85 | F2 (0.47) | F2F10EGFRPLGPLAU | |
| SCHEMBL7493245 | 0.85 | F2 (0.43) | F2F10EGFRPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6232325-B1 | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. | 2001-05-15 | — | — | US | disclosed |
| US-6177473-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-01-23 | — | — | US | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |