Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | PLG | P00747 | 6/20 | 0.33 |
| ▸ | PLAU | P00749 | 6/20 | 0.33 |
| ▸ | PLAT | P00750 | 5/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413956 | 0.88 | F10 (0.41) | F2F10PLGPLAUPLAT | |
| SCHEMBL7483993 | 0.88 | F10 (0.47) | F2F10PLGPLAUPLAT | |
| SCHEMBL7486887 | 0.87 | F2 (0.44) | F2F10PLGPLAUPLAT | |
| SCHEMBL7487818 | 0.86 | MRGPRX4 (0.34) | PTGER1SLC6A9 | |
| SCHEMBL7485110 | 0.84 | F10 (0.47) | F2F10PLGPLAUPLAT | |
| SCHEMBL7490911 | 0.84 | F10 (0.46) | F2F10PLGPLAUPLAT | |
| SCHEMBL7494259 | 0.82 | F10 (0.44) | F2F10PLGPLAUPLAT | |
| SCHEMBL7492995 | 0.82 | F10 (0.42) | F2F10PLGPLAUPLAT | |
| SCHEMBL7414461 | 0.82 | F2 (0.49) | F2F10PLGPLAUPLAT | |
| SCHEMBL7496461 | 0.81 | F2 (0.47) | F2F10PLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |