Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.60 |
| ▸ | TCF4 | P15884 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487007 | 1.00 | FFAR1 (0.66) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7491497 | 0.97 | FFAR1 (0.67) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7491489 | 0.97 | FFAR1 (0.67) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7493574 | 0.95 | CISD1 (0.64) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7493581 | 0.95 | CISD1 (0.64) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7490262 | 0.92 | CISD1 (0.65) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7490259 | 0.92 | CISD1 (0.65) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7489759 | 0.90 | FFAR1 (0.64) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL7489754 | 0.90 | FFAR1 (0.64) | FFAR1MAPTKDM4EKMT2ACTNNB1 | |
| SCHEMBL12008730 | 0.90 | FFAR1 (0.71) | FFAR1MAPTKDM4EKMT2ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192143-A1 | RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000076987-A1 | RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| EP-1192143-A1 | RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076987-A1 | RHODANINE DERIVATIVES FOR USE IN A METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |