Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354061 | 0.82 | PNMT (0.36) | — | |
| SCHEMBL11154284 | 0.70 | SLC6A4 (0.30) | — | |
| SCHEMBL11154285 | 0.70 | SLC6A4 (0.30) | — | |
| SCHEMBL1479641 | 0.70 | — | — | |
| SCHEMBL5285093 | 0.70 | MAPT (0.39) | — | |
| SCHEMBL10843829 | 0.70 | SLC5A2 (0.35) | — | |
| SCHEMBL1465771 | 0.68 | CYP2D6 (0.54) | — | |
| SCHEMBL29642903 | 0.68 | TAAR1 (0.60) | — | |
| SCHEMBL50478 | 0.68 | TAAR1 (0.60) | — | |
| Methylene Chloride SCHEMBL29186228 | 0.67 | TAAR1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242075-A4 | INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1242075-A2 | INDOLE COMPOUNDS | SmithKline Beecham Corporation (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001030752-A2 | INDOLE COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-03 | — | — | WO | disclosed |