Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492084 | 0.95 | ADORA2A (0.35) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL7488641 | 0.94 | ADORA2A (0.34) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL7489579 | 0.92 | ADORA2A (0.32) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL7495203 | 0.84 | CDK1 (0.33) | ADORA2AADORA1DYRK1A | |
| SCHEMBL7488843 | 0.78 | CNOT7 (0.43) | ADORA2AADORA2BADORA1PDE4APDE4B | |
| SCHEMBL7492592 | 0.77 | TSHR (0.45) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL7492336 | 0.76 | PDE4A (0.39) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL7491743 | 0.76 | TSHR (0.41) | ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL7486552 | 0.76 | CHRM2 (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7486698 | 0.75 | TSHR (0.41) | ADORA2AADORA2BADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |