Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483813 | 0.95 | CYP4F2 (0.51) | CYP4F2CYP4A11KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7490164 | 0.95 | CYP4F2 (0.51) | CYP4F2CYP4A11KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7483826 | 0.95 | CYP4F2 (0.51) | CYP4F2CYP4A11KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9255724 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL1519271 | 0.83 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1L3MBTL1GAA | |
| SCHEMBL7484765 | 0.82 | HPGD (0.49) | KMT2ACYP3A4ALDH1A1L3MBTL1GAA | |
| SCHEMBL7489974 | 0.82 | HPGD (0.49) | KMT2ACYP3A4ALDH1A1L3MBTL1GAA | |
| SCHEMBL7203233 | 0.82 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1L3MBTL1GAA | |
| SCHEMBL7484752 | 0.82 | HPGD (0.49) | KMT2ACYP3A4ALDH1A1L3MBTL1GAA | |
| SCHEMBL7204613 | 0.81 | CYP4F2 (0.46) | CYP4F2CYP4A11KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825189-B1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6130243-A | PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIABETES, HYPERGLYCEMIA AND OBESITY IN MAMMALS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0825189-A1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |